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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Gstm1tm1Kfuj
targeted mutation 1, Kazunori Fujimoto
MGI:3828070
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Gstm1tm1Kfuj/Gstm1tm1Kfuj involves: 129S1/Sv * C57BL/6J MGI:3828071


Genotype
MGI:3828071
hm1
Allelic
Composition		 Gstm1tm1Kfuj/Gstm1tm1Kfuj
Genetic
Background		 involves: 129S1/Sv * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gstm1tm1Kfuj mutation (0 available); any Gstm1 mutation (25 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
homeostasis/metabolism
abnormal xenobiotic pharmacokinetics ( J:143553 )
• retention of 1,2-dichloro-4-nitrobenzene (DCNB) in plasma over the course of 24 hours following a single oral dose is around 5 times higher than controls
• peak concentrations of the major DCNB metabolite is half that of controls
• homozygotes are otherwise normal and are fertile




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory