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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Gt(ROSA)26Sortm3(Gli3)Amc
targeted mutation 3, Andrew P McMahon
MGI:3828280
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cn1
Gt(ROSA)26Sortm3(Gli3)Amc/Gt(ROSA)26Sor+
Tg(Prrx1-cre)1Cjt/0
involves: 129 * C57BL/6J * CBA * SJL/J * Swiss Webster MGI:3828285


Genotype
MGI:3828285
cn1
Allelic
Composition
Gt(ROSA)26Sortm3(Gli3)Amc/Gt(ROSA)26Sor+
Tg(Prrx1-cre)1Cjt/0
Genetic
Background
involves: 129 * C57BL/6J * CBA * SJL/J * Swiss Webster
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gt(ROSA)26Sortm3(Gli3)Amc mutation (1 available); any Gt(ROSA)26Sor mutation (993 available)
Tg(Prrx1-cre)1Cjt mutation (2 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
limbs/digits/tail
• mice exhibit variable preaxial forelimb polydactyly
• limb truncation

skeleton
• mice exhibit reduced mineralization





Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory