About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Apctm1Tyj
targeted mutation 1, Tyler Jacks
MGI:3829069
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Apctm1Tyj/Apctm1Tyj involves: 129P2/OlaHsd * C57BL/6 MGI:4441382
cn2
 		Apctm1Tyj/Apc+
Tg(Vil1-cre)20Syr/0 		involves: C57BL/6 * DBA/2 MGI:4461182


Genotype
MGI:4441382
hm1
Allelic
Composition		 Apctm1Tyj/Apctm1Tyj
Genetic
Background		 involves: 129P2/OlaHsd * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Apctm1Tyj mutation (1 available); any Apc mutation (158 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
normal phenotype
no abnormal phenotype detected ( J:159014 )
• homozygous mice are viable, fertile, normal in size and do not display any gross physical or behavioral abnormalities




Genotype
MGI:4461182
cn2
Allelic
Composition		 Apctm1Tyj/Apc+
Tg(Vil1-cre)20Syr/0
Genetic
Background		 involves: C57BL/6 * DBA/2
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Apctm1Tyj mutation (1 available); any Apc mutation (158 available)
Tg(Vil1-cre)20Syr mutation (4 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
neoplasm
increased intestinal adenoma incidence ( J:160399 )
• develop several lesions in the small intestines and colons by 4 - 5 months of age
increased colon adenoma incidence ( J:160399 )
• develop by 4 - 5 months of age

digestive/alimentary system
increased intestinal adenoma incidence ( J:160399 )
• develop several lesions in the small intestines and colons by 4 - 5 months of age
increased colon adenoma incidence ( J:160399 )
• develop by 4 - 5 months of age




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
10/29/2024
MGI 6.24 		The Jackson Laboratory