cellular
• following antigen stimulation in fetal liver chimeras, T cell proliferation is less than in similarly treated wild-type chimeras
• however, treatment with IL-2 results in normal proliferation rates
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mortality/aging
• no mice are present at weaning
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• mice die at birth
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hematopoietic system
• following antigen stimulation in fetal liver chimeras, T cell proliferation is less than in similarly treated wild-type chimeras
• however, treatment with IL-2 results in normal proliferation rates
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• in fetal liver chimeras, the percentage of B cell and CD11b+ cells in the lymph nodes and spleens is slightly lower than in wild-type chimeras
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• in fetal liver chimeras, the number of T cells in the spleen is larger than in wild-type chimeras
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• in fetal liver chimeras, the percentage of CD4+ and CD8+ cells in the lymph nodes and spleens is increased compared to in wild-type chimeras
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• in fetal liver chimeras, the percentage of CD4+ and CD8+ cells in the lymph nodes and spleens is increased compared to in wild-type chimeras
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• fetal liver chimeras exhibit decreased IgG1, IgG2 (a and b) and IgG3 both pre- and post-immunization compared to wild-type chimeras
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• fetal liver chimeras exhibit decreased IgG1, IgG2 (a and b) and IgG3 both pre- and post-immunization compared to wild-type chimeras
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• fetal liver chimeras exhibit decreased IgG1, IgG2 (a and b) and IgG3 both pre- and post-immunization compared to wild-type chimeras
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• in fetal liver chimeras following immunization
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immune system
• following antigen stimulation in fetal liver chimeras, T cell proliferation is less than in similarly treated wild-type chimeras
• however, treatment with IL-2 results in normal proliferation rates
|
• in fetal liver chimeras, the percentage of B cell and CD11b+ cells in the lymph nodes and spleens is slightly lower than in wild-type chimeras
|
• in fetal liver chimeras, the number of T cells in the spleen is larger than in wild-type chimeras
|
• in fetal liver chimeras, the percentage of CD4+ and CD8+ cells in the lymph nodes and spleens is increased compared to in wild-type chimeras
|
• in fetal liver chimeras, the percentage of CD4+ and CD8+ cells in the lymph nodes and spleens is increased compared to in wild-type chimeras
|
• fetal liver chimeras exhibit decreased IgG1, IgG2 (a and b) and IgG3 both pre- and post-immunization compared to wild-type chimeras
|
• fetal liver chimeras exhibit decreased IgG1, IgG2 (a and b) and IgG3 both pre- and post-immunization compared to wild-type chimeras
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• fetal liver chimeras exhibit decreased IgG1, IgG2 (a and b) and IgG3 both pre- and post-immunization compared to wild-type chimeras
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• in fetal liver chimeras following immunization
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• in T cells from fetal liver chimeras that were cultured with anti-CD3 and anti-CD28
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