Analysis Tools
hearing/vestibular/ear
| N |
• despite defects in the semicircular canal, mice exhibit normal hearing
|
|
• at E12, basal lamina is missing or disrupted in the lateral pouch and epithelium throughout the lateral pouch is thin unlike in wild-type mice
• at E12.5, fusion of the lateral pouch is expanded and accelerated compared to in wild-type mice
• however, otic vessel patterning is normal
|
|
• canal epithelium is absent unlike in wild-type mice
|
|
• truncation of the lateral semicircular canal occurs at E12.5 following expanded and accelerated fusion of the lateral pouches compared to in wild-type mice
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behavior/neurological
head tossing
(
J:142510
)
craniofacial
short snout
(
J:142510
)
growth/size/body
short snout
(
J:142510
)
