Phenotypes associated with this allele

• Allele Symbol: Pthlh^tm1Broa
• Allele Name: targeted mutation 1, Arthur E Broadus
• Allele ID: MGI:3829430
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Pthlh^tm1Broa/Pthlh^tm1Broa	involves: 129S1/Sv * C57BL/6J * CD-1	MGI:3829433

Genotype
MGI:3829433

hm1

• Allelic Composition: Pthlh^tm1Broa/Pthlh^tm1Broa
• Genetic Background: involves: 129S1/Sv * C57BL/6J * CD-1

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

skeleton

abnormal long bone epiphyseal plate proliferative zone ( J:128121 )

• the growth plate of proximal tibias from E18.5 embryos is half that of controls with a marked reduction in the chondrocyte columns

short ribs ( J:128121 )

• ribs of newborn mice are shorter

chondrodystrophy ( J:128121 )

• newborn mice exhibit a chondrodysplastic phenotype

• the growth plate of proximal tibias from E18.5 embryps is half that of controls with a marked reduction in the chondrocyte columns