About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Tcrbtm6Slek
targeted mutation 6, Barry P Sleckman
MGI:3829441
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Tcrbtm6Slek/Tcrbtm6Slek Not Specified MGI:3829445
ht2
 		Tcrbtm1Slek/Tcrbtm6Slek Not Specified MGI:3829447


Genotype
MGI:3829445
hm1
Allelic
Composition		 Tcrbtm6Slek/Tcrbtm6Slek
Genetic
Background		 Not Specified
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tcrbtm6Slek mutation (0 available); any Tcrb mutation (97 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
abnormal T cell receptor beta chain V(D)J recombination ( J:143738 )
• rearrangement fails to occur at the Tcrb locus

hematopoietic system
abnormal T cell receptor beta chain V(D)J recombination ( J:143738 )
• rearrangement fails to occur at the Tcrb locus




Genotype
MGI:3829447
ht2
Allelic
Composition		 Tcrbtm1Slek/Tcrbtm6Slek
Genetic
Background		 Not Specified
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tcrbtm1Slek mutation (0 available); any Tcrb mutation (97 available)
Tcrbtm6Slek mutation (0 available); any Tcrb mutation (97 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
abnormal T cell receptor beta chain V(D)J recombination ( J:143738 )
• rearrangement of the V gene segments to the D gene segment on the Tcrbtm6Slek allele occurs at much reduced rate

hematopoietic system
abnormal T cell receptor beta chain V(D)J recombination ( J:143738 )
• rearrangement of the V gene segments to the D gene segment on the Tcrbtm6Slek allele occurs at much reduced rate




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory