Phenotypes associated with this allele

• Allele Symbol: Xist^tm5Sado
• Allele Name: targeted mutation 5, Takashi Sado
• Allele ID: MGI:3829654
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
ht1	Xist^tm5Sado/Xist^+	involves: 129S4/SvJae	MGI:3829657

Genotype
MGI:3829657

ht1

• Allelic Composition: Xist^tm5Sado/Xist⁺
• Genetic Background: involves: 129S4/SvJae

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

prenatal lethality, incomplete penetrance ( J:142921 )

♀ • when this allele is inherited paternally, only 2 XO females were born

♀ • however, birth rates are normal when this allele is inherited maternally

embryo

abnormal embryo development ( J:142921 )

♀ • when this allele is inherited paternally, female mice exhibit an abnormal morphology at E6.5

decreased embryo size ( J:142921 )

♀ • when this allele is inherited paternally, mice are stunted at E6.5

abnormal extraembryonic ectoderm morphology ( J:142921 )

♀ • when this allele is inherited paternally, female mice exhibit abnormal extraembryonic ectoderm at E6.5

cellular

abnormal imprinting ( J:142921 )

♀ • when this allele is inherited paternally

growth/size/body

decreased embryo size ( J:142921 )

♀ • when this allele is inherited paternally, mice are stunted at E6.5