All Phenotypes Xist<tm5Sado> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Xist^tm5Sado
targeted mutation 5, Takashi Sado
MGI:3829654

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
ht1	Xist^tm5Sado/Xist⁺	involves: 129S4/SvJae	MGI:3829657

Allelic Composition	Xist^tm5Sado/Xist⁺
Genetic Background	involves: 129S4/SvJae

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Xist^tm5Sado mutation (1 available); any Xist mutation (8 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

• when this allele is inherited paternally, only 2 XO females were born

• however, birth rates are normal when this allele is inherited maternally

embryo

abnormal embryo development ( J:142921 )

• when this allele is inherited paternally, female mice exhibit an abnormal morphology at E6.5

decreased embryo size ( J:142921 )

• when this allele is inherited paternally, mice are stunted at E6.5

• when this allele is inherited paternally, female mice exhibit abnormal extraembryonic ectoderm at E6.5

cellular

abnormal imprinting ( J:142921 )

• when this allele is inherited paternally

growth/size/body

decreased embryo size ( J:142921 )

• when this allele is inherited paternally, mice are stunted at E6.5

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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