Phenotypes associated with this allele

• Allele Symbol: Rictor^tm1Rueg
• Allele Name: targeted mutation 1, Markus Ruegg
• Allele ID: MGI:3829768
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
cn1	Rictor^tm1Rueg/Rictor^tm1Rueg Tg(ACTA1-cre)1Mll/0	involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL	MGI:3829871
cn2	Rictor^tm1Rueg/Rictor^tm1Rueg Rptor^tm1Rueg/Rptor^tm1Rueg Tg(ACTA1-cre)1Mll/0	involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL	MGI:3829873

Genotype
MGI:3829871

cn1

• Allelic Composition: Rictor^tm1Rueg/Rictor^tm1Rueg; Tg(ACTA1-cre)1Mll/0
• Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

mortality/aging ( J:143748 )

N • mice exhibit a normal lifespan

growth/size/body

increased body weight ( J:143748 )

• slightly at higher ages

muscle

muscle phenotype ( J:143748 )

N • mice exhibit normal muscle morphology

Genotype
MGI:3829873

cn2

• Allelic Composition: Rictor^tm1Rueg/Rictor^tm1Rueg; Rptor^tm1Rueg/Rptor^tm1Rueg; Tg(ACTA1-cre)1Mll/0
• Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL

mortality/aging

premature death ( J:143748 )

• mice exhibit a phenotype indistinguishable from 4932417H02Rik^tm1Rueg homozygotes

muscle

abnormal muscle morphology ( J:143748 )

• mice exhibit a phenotype indistinguishable from 4932417H02Rik^tm1Rueg homozygotes

abnormal muscle physiology ( J:143748 )

• mice exhibit a phenotype indistinguishable from 4932417H02Rik^tm1Rueg homozygotes

adipose tissue

abnormal adipose tissue morphology ( J:143748 )

• mice exhibit a phenotype indistinguishable from 4932417H02Rik^tm1Rueg homozygotes

growth/size/body

abnormal postnatal growth/weight/body size ( J:143748 )

• mice exhibit a phenotype indistinguishable from 4932417H02Rik^tm1Rueg homozygotes