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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Drd1tm1Tono
targeted mutation 1, Taketoshi Ono
MGI:3829942
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Drd1tm1Tono/Drd1tm1Tono B6.129S-Drd1tm1Tono MGI:3829985


Genotype
MGI:3829985
hm1
Allelic
Composition
Drd1tm1Tono/Drd1tm1Tono
Genetic
Background
B6.129S-Drd1tm1Tono
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Drd1tm1Tono mutation (12 available); any Drd1 mutation (70 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
nervous system
• in a familiar environment, place cells exhibit reduced response to distal cues and increased response to proximal cues compared to wild-type cells
• in a novel environment, fewer cells change their firing fields compared to wild-type cells
• in a novel environment, no place cells respond to distal cues unlike wild-type cells that increase their response and fewer than normal cells follow the rotation of proximal cues





Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory