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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Myo18btm1Jyo
targeted mutation 1, Jun Yokota
MGI:3829997
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Myo18btm1Jyo/Myo18btm1Jyo involves: C57BL/6J MGI:3830000


Genotype
MGI:3830000
hm1
Allelic
Composition
Myo18btm1Jyo/Myo18btm1Jyo
Genetic
Background
involves: C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Myo18btm1Jyo mutation (1 available); any Myo18b mutation (115 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging

cardiovascular system
• the lumens of the right and left cardinal veins are morbidly enlarged
• at E10.5, alignment of parallel thick and thin filaments is disorganized and the distribution of thick and thin filaments is unbalanced
• the lumen is morbidly enlarged
• variable degrees of pericardial effusion are seen
• some embryos show severe hemorrhage in the cardiac and ventral body wall regions

muscle

homeostasis/metabolism
• variable degrees of pericardial effusion are seen





Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
10/29/2024
MGI 6.24
The Jackson Laboratory