About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Myo18btm1Jyo
targeted mutation 1, Jun Yokota
MGI:3829997
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Myo18btm1Jyo/Myo18btm1Jyo involves: C57BL/6J MGI:3830000


Genotype
MGI:3830000
hm1
Allelic
Composition
Myo18btm1Jyo/Myo18btm1Jyo
Genetic
Background
involves: C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Myo18btm1Jyo mutation (1 available); any Myo18b mutation (115 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging

cardiovascular system
• the lumens of the right and left cardinal veins are morbidly enlarged
• at E10.5, alignment of parallel thick and thin filaments is disorganized and the distribution of thick and thin filaments is unbalanced
• the lumen is morbidly enlarged
• variable degrees of pericardial effusion are seen
• some embryos show severe hemorrhage in the cardiac and ventral body wall regions

muscle

homeostasis/metabolism
• variable degrees of pericardial effusion are seen





Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
11/12/2024
MGI 6.24
The Jackson Laboratory