Analysis Tools
immune system
| N |
• despite impaired anaphylaxis, mice exhibit normal mast cell development
|
|
• calcium concentrations in antigen-challenged bone marrow-derived mast cells is less than in wild-type cells
|
|
• when challenged with DNP-HAS, mice exhibit reduced histamine secretion compared to similarly treated wild-type mice
• bone marrow-derived mast cells exhibit reduced antigen to IgE antibody mediated cross-linking compared to wild-type cells
|
|
• in an assay for IgE-dependent passive systemic anaphylaxis using DNP-HSA, mice exhibit a smaller decrease in core body temperature and reduced histamine secretion compared to similarly treated wild-type mice
|
hematopoietic system
|
• calcium concentrations in antigen-challenged bone marrow-derived mast cells is less than in wild-type cells
|
|
• when challenged with DNP-HAS, mice exhibit reduced histamine secretion compared to similarly treated wild-type mice
• bone marrow-derived mast cells exhibit reduced antigen to IgE antibody mediated cross-linking compared to wild-type cells
|
cellular
|
• when challenged with DNP-HAS, mice exhibit reduced histamine secretion compared to similarly treated wild-type mice
• bone marrow-derived mast cells exhibit reduced antigen to IgE antibody mediated cross-linking compared to wild-type cells
|
