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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Bub1Gt(XG453)Byg
gene trap XG453, BayGenomics
MGI:3830862
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
ht1
 		Bub1Gt(XG453)Byg/Bub1+ involves: 129P2/OlaHsd * C57BL/6J MGI:3830994
ht2
 		Bub1Gt(XG453)Byg/Bub1tm1.1Tvd involves: 129P2/OlaHsd * C57BL/6J MGI:3830995


Genotype
MGI:3830994
ht1
Allelic
Composition		 Bub1Gt(XG453)Byg/Bub1+
Genetic
Background		 involves: 129P2/OlaHsd * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Bub1Gt(XG453)Byg mutation (0 available); any Bub1 mutation (52 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cellular
maternal effect ( J:143035 )
• 90% of mice of all genotypes are resorbed by E14.




Genotype
MGI:3830995
ht2
Allelic
Composition		 Bub1Gt(XG453)Byg/Bub1tm1.1Tvd
Genetic
Background		 involves: 129P2/OlaHsd * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Bub1Gt(XG453)Byg mutation (0 available); any Bub1 mutation (52 available)
Bub1tm1.1Tvd mutation (0 available); any Bub1 mutation (52 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
embryonic lethality during organogenesis, complete penetrance ( J:143035 )
• when Bub1Gt(XG453)Byg is inherited paternally, no mice are present at E11.5




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory