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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Ptpn3tm1Pdk
targeted mutation 1, Phillip D King
MGI:3830864
Summary 3 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Ptpn3tm1Pdk/Ptpn3tm1Pdk C57BL/6-Ptpn3tm1Pdk MGI:3830967
cx2
Ptpn13tm1Wjh/Ptpn13tm1Wjh
Ptpn3tm1Pdk/Ptpn3tm1Pdk
Ptpn4Gt(OST146128)Lex/Ptpn4Gt(OST146128)Lex
involves: 129P2/OlaHsd * 129S5/SvEvBrd * C57BL/6 MGI:3831001
cx3
Ptpn3tm1Pdk/Ptpn3tm1Pdk
Ptpn4Gt(OST146128)Lex/Ptpn4Gt(OST146128)Lex
involves: 129S5/SvEvBrd * C57BL/6 MGI:3831000


Genotype
MGI:3830967
hm1
Allelic
Composition
Ptpn3tm1Pdk/Ptpn3tm1Pdk
Genetic
Background
C57BL/6-Ptpn3tm1Pdk
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ptpn3tm1Pdk mutation (0 available); any Ptpn3 mutation (170 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
normal phenotype
• mice are born in expected Mendelian ratios, have normal numbers and ratios of T cells in primary and secondary lymphoid organs, and show no signs of spontaneous T cell activation with increasing age




Genotype
MGI:3831001
cx2
Allelic
Composition
Ptpn13tm1Wjh/Ptpn13tm1Wjh
Ptpn3tm1Pdk/Ptpn3tm1Pdk
Ptpn4Gt(OST146128)Lex/Ptpn4Gt(OST146128)Lex
Genetic
Background
involves: 129P2/OlaHsd * 129S5/SvEvBrd * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ptpn13tm1Wjh mutation (0 available); any Ptpn13 mutation (96 available)
Ptpn3tm1Pdk mutation (0 available); any Ptpn3 mutation (170 available)
Ptpn4Gt(OST146128)Lex mutation (0 available); any Ptpn4 mutation (50 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
immune system
N
• mice exhibit normal immune compartment and T-helper cell differentiation




Genotype
MGI:3831000
cx3
Allelic
Composition
Ptpn3tm1Pdk/Ptpn3tm1Pdk
Ptpn4Gt(OST146128)Lex/Ptpn4Gt(OST146128)Lex
Genetic
Background
involves: 129S5/SvEvBrd * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ptpn3tm1Pdk mutation (0 available); any Ptpn3 mutation (170 available)
Ptpn4Gt(OST146128)Lex mutation (0 available); any Ptpn4 mutation (50 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
immune system
N
• mice exhibit normal immune compartment and T cell proliferation





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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory