Phenotypes associated with this allele

• Allele Symbol: Tg(Prnp-ATN1)124Dbo
• Allele Name: transgene insertion 124, David R Borchelt
• Allele ID: MGI:3831350
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
tg1	Tg(Prnp-ATN1)124Dbo/?	involves: C3H * C57BL/6	MGI:5056392

Genotype
MGI:5056392

tg1

• Allelic Composition: Tg(Prnp-ATN1)124Dbo/?
• Genetic Background: involves: C3H * C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

increased aggression ( J:70362 )

• phenotype is reported to be similar to Tg(Prnp-ATN1)150Dbo, but onset of symptoms occurs at 8-12 months

tremors ( J:70362 )

• phenotype is reported to be similar to Tg(Prnp-ATN1)150Dbo, but onset of symptoms occurs at 8-12 months

ataxia ( J:70362 )

• phenotype is reported to be similar to Tg(Prnp-ATN1)150Dbo, but onset of symptoms occurs at 8-12 months

impaired limb coordination ( J:70362 )

• phenotype is reported to be similar to Tg(Prnp-ATN1)150Dbo, but onset of symptoms occurs at 8-12 months

hyperactivity ( J:70362 )

• phenotype is reported to be similar to Tg(Prnp-ATN1)150Dbo, but onset of symptoms occurs at 8-12 months

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
dentatorubral-pallidoluysian atrophy		DOID:0060162	OMIM:125370	J:70362