Phenotypes associated with this allele

• Allele Symbol: Id1^tm1Xhsu
• Allele Name: targeted mutation 1, Xiao-Hong Sun
• Allele ID: MGI:3831561
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Id1^tm1Xhsu/Id1^tm1Xhsu	B6.129X1-Id1^tm1Xhsu	MGI:3831663

Genotype
MGI:3831663

hm1

• Allelic Composition: Id1^tm1Xhsu/Id1^tm1Xhsu
• Genetic Background: B6.129X1-Id1^tm1Xhsu

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

hematopoietic system

decreased hematopoietic stem cell number ( J:144696 )

• there is a 45% reduction in the number of long-term HSC in whole bone marrow cells based on the ability to generate multilineage engraftment after serial transplantation in irradiated hosts

• similar results are observed when fractions of bone marrow cells enriched in stem cells are used in serial transplantation of irradiated hosts

• multilineage engraftment in the primary bone marrow transplant is the same when mutant or wild-type mice are the donors, indicating short term HSC cells are unaffected