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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Plxna1tm2Tmj
targeted mutation 2, Thomas M Jessell
MGI:3831875
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cn1
 		Plxna1tm2Tmj/Plxna1tm2Tmj
Tg(PLAT-cre)116Sdu/0 		involves: 129S/SvEv * C57BL/6J MGI:3831889


Genotype
MGI:3831889
cn1
Allelic
Composition		 Plxna1tm2Tmj/Plxna1tm2Tmj
Tg(PLAT-cre)116Sdu/0
Genetic
Background		 involves: 129S/SvEv * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Plxna1tm2Tmj mutation (0 available); any Plxna1 mutation (75 available)
Tg(PLAT-cre)116Sdu mutation (0 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
abnormal oligodendrocyte morphology ( J:144660 )
• MAG+ oligodendrocytes are misplaced in the vicinity of the proprioceptive axonal shafts in the superficial dorsal horn unlike in wild-type mice
abnormal proprioceptive neuron morphology ( J:144660 )
• at P0, the proprioceptive axons are displaced into the neuropil of the dorsal spinal cord unlike in wild-type mice




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory