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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Tg(ABCA1)1Hgc
transgene insertion 1, Human Genome Center
MGI:3832216
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
tg1
Tg(ABCA1)1Hgc/? involves: FVB MGI:5056311


Genotype
MGI:5056311
tg1
Allelic
Composition
Tg(ABCA1)1Hgc/?
Genetic
Background
involves: FVB
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tg(ABCA1)1Hgc mutation (1 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
cellular
• mice exhibit a 2 fold increase in macrophage Apoa1-mediated cholesterol efflux, but no accompanying alteration in plasma high density lipoprotein

homeostasis/metabolism
• mice exhibit a 2 fold increase in macrophage Apoa1-mediated cholesterol efflux, but no accompanying alteration in plasma high density lipoprotein





Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory