Analysis Tools
respiratory system
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• cellularity in BAL fluid is almost double that of controls in mice with cre induction
• increase in cellularity is also found after bleomycin injury of the lung
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• there is about a 2-fold increase in the number of type II alveolar cells present in the lungs of mice treated with doxycycline
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• alveolar septa are thickened with increased deposition of collagen IV in mice with cre induction
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• bleomycin injury of the lungs leads to less fibrosis three weeks later due to impaired myofibroblast accumulation and reduced type I collagen response
• the number of myofibroblast per field is 4-5 fold less than in controls after bleomycin injury
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• there is a trend towards less compliance in these mice after bleomycin injury than in controls
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growth/size/body
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• cellularity in BAL fluid is almost double that of controls in mice with cre induction
• increase in cellularity is also found after bleomycin injury of the lung
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