Phenotypes associated with this allele

• Allele Symbol: Plcg2^tm1Ichi
• Allele Name: targeted mutation 1, Hirotake Ichise
• Allele ID: MGI:3833397
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Plcg2^tm1Ichi/Plcg2^tm1Ichi	involves: 129 * C57BL/6	MGI:3833401

Genotype
MGI:3833401

hm1

• Allelic Composition: Plcg2^tm1Ichi/Plcg2^tm1Ichi
• Genetic Background: involves: 129 * C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

premature death ( J:143529 )

• die spontaneously by bleeding during development or in adulthood

homeostasis/metabolism

chylous ascites ( J:143529 )

immune system

abnormal lymphatic vessel morphology ( J:143529 )

• blood-filled lymphatic vessels in the intestine, heart, diaphragm, and skin in adult

• lymphatic vessels of homozygous mutants are blood-filled by mid-gestation

• occasional fusion between blood and lymphatic vessels

cardiovascular system

internal hemorrhage ( J:143529 )

• during development and in adulthood