Analysis Tools|
Allele Symbol Allele Name Allele ID |
Il17ftm1Awai targeted mutation 1, Ari Waisman MGI:3833572 |
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| Summary |
2 genotypes
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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• there is no difference in onset or severity of experimental autoimmune encephalomyelitis induced by myelin oligodendrocyte glycoprotein peptide (MOG) compared to controls even when IL-17A was neutralized by antibody treatment
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• Th17 polarized splenocytes do not produce IL-17F and produce less IL-17A in vitro
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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• Th17-polarized splenocytes produce less IL-17F than controls
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 11/19/2024 MGI 6.24 |
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