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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Olig3tm2(cre/ERT2)Cbm
targeted mutation 2, Carmen Birchmeier
MGI:3833733
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
ht1
Olig3tm1Tre/Olig3tm2(cre/ERT2)Cbm Not Specified MGI:3833734


Genotype
MGI:3833734
ht1
Allelic
Composition
Olig3tm1Tre/Olig3tm2(cre/ERT2)Cbm
Genetic
Background
Not Specified
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Olig3tm1Tre mutation (0 available); any Olig3 mutation (9 available)
Olig3tm2(cre/ERT2)Cbm mutation (0 available); any Olig3 mutation (9 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
nervous system
• the nucleus of the solitary tract did not form
• precerebellar nuclei, such as the inferior olivary nucleus, were absent or small
• the fate of dA4 neurons is not correctly determined, resulting in the absence of climbing finer neurons of the inferior olivary nucleus
• the fate of dA3 neurons was not correctly determined, resulting in the absence of the nucleus of the solitary tract and the area postrema
• ectopic Lbx1+ neurons appeared in the alar plate

cellular
• the nucleus of the solitary tract did not form
• precerebellar nuclei, such as the inferior olivary nucleus, were absent or small





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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
10/29/2024
MGI 6.24
The Jackson Laboratory