All Phenotypes Tg(Myh6-Pln)22Egk MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Tg(Myh6-Pln)22Egk
transgene insertion 22, Evangelia G Kranias
MGI:3833965

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
cx1	Pln^tm1Egk/Pln^tm1Egk Tg(Myh6-Pln)22Egk/?	involves: 129S2/SvPas	MGI:5051956

Allelic Composition	Pln^tm1Egk/Pln^tm1Egk Tg(Myh6-Pln)22Egk/?
Genetic Background	involves: 129S2/SvPas

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Pln^tm1Egk mutation (7 available); any Pln mutation (16 available)
Tg(Myh6-Pln)22Egk mutation (1 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

cardiovascular system

cardiovascular system phenotype ( J:66084 )

• ventricular myocytes exhibit increases in shortening fraction, rates of shortening and de-lengthening following maximal stimulation with the beta adrenergic agonist, isoproterenol, however, these increases are similar to those observed in mice expressing Pln^tm1Egk Tg(Myh6-Pln)1Egk (wild type phospholambin)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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