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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Slc4a1tm1Dmb
targeted mutation 1, David M Bodine
MGI:3834176
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Slc4a1tm1Dmb/Slc4a1tm1Dmb involves: 129S6/SvEvTac MGI:3834177


Genotype
MGI:3834177
hm1
Allelic
Composition
Slc4a1tm1Dmb/Slc4a1tm1Dmb
Genetic
Background
involves: 129S6/SvEvTac
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Slc4a1tm1Dmb mutation (0 available); any Slc4a1 mutation (54 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
hematopoietic system
• increase in the percentage of Ter119 positive erythroid cells in the bone marrow
• cells are smaller compared to controls
• contain a higher percentage of spherocytes and stomatocytes
• almost half of all red blood cells are abnormally shaped compared to less than 5% in wild-type controls
• contain a higher percentage of spherocytes and stomatocytes
• significantly higher percentage of reticulocytes in the peripheral blood
• increase in the percentage of Ter119 positive erythroid cells in the spleen
• increase in the osmotic fragility of erythrocytes

immune system
• increase in the percentage of Ter119 positive erythroid cells in the spleen





Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory