Allele Symbol Allele Name Allele ID |
Kif22tm1.1Tya targeted mutation 1.1, Tadashi Yamamoto MGI:3834595 |
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Summary |
2 genotypes
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♀ | phenotype observed in females |
♂ | phenotype observed in males |
N | normal phenotype |
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♀ | phenotype observed in females |
♂ | phenotype observed in males |
N | normal phenotype |
• 50% fewer than expected blastocysts are recovered at E3.5
• however, the number of 2 to 8 cell staged mice is normal
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• first and second polar bodies are retained within fertilized oocyte and results in multi-pronuclei at the 1-cell stage
• anaphase chromosome compaction results in the formation of multinucleated cells during oocyte meiosis II and early embryogenesis
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• anaphase chromosome compaction results in the formation of multinucleated cells during oocyte meiosis II and early embryogenesis
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 08/02/2024 MGI 6.24 |
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