All Phenotypes Gt(ROSA)26Sor<tm1(Dkk1)Flng> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Gt(ROSA)26Sor^{tm1(Dkk1)Flng}
targeted mutation 1, Fanxin Long
MGI:3834604

Summary

2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
cn1	Gt(ROSA)26Sor^{tm1(Dkk1)Flng}/Gt(ROSA)26Sor⁺ Rac1^tm1Djk/Rac1⁺ Tg(Msx2-cre)5Rem/0	involves: 129S4/SvJae * 129X1/SvJ	MGI:3834606
cn2	Gt(ROSA)26Sor^{tm1(Dkk1)Flng}/Gt(ROSA)26Sor^{tm1(Dkk1)Flng} Tg(Msx2-cre)5Rem/0	involves: 129X1/SvJ	MGI:3834605

Allelic Composition	Gt(ROSA)26Sor^{tm1(Dkk1)Flng}/Gt(ROSA)26Sor⁺ Rac1^tm1Djk/Rac1⁺ Tg(Msx2-cre)5Rem/0
Genetic Background	involves: 129S4/SvJae * 129X1/SvJ

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gt(ROSA)26Sor^{tm1(Dkk1)Flng} mutation (0 available); any Gt(ROSA)26Sor mutation (993 available)
Rac1^tm1Djk mutation (1 available); any Rac1 mutation (24 available)
Tg(Msx2-cre)5Rem mutation (2 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

limbs/digits/tail

short forelimb ( J:145305 )

• severe forelimb truncation

absent hindlimb ( J:145305 )

Allelic Composition	Gt(ROSA)26Sor^{tm1(Dkk1)Flng}/Gt(ROSA)26Sor^{tm1(Dkk1)Flng} Tg(Msx2-cre)5Rem/0
Genetic Background	involves: 129X1/SvJ

Find Mice

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

limbs/digits/tail

short forelimb ( J:145305 )

• partial forelimb truncation

absent hindlimb ( J:145305 )

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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