Phenotypes associated with this allele

• Allele Symbol: Tg(SFTPC-EML4/ALK)502-4Hima
• Allele Name: transgene insertion 502-4, Hiroyuki Mano
• Allele ID: MGI:3834680
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
tg1	Tg(SFTPC-EML4/ALK)502-4Hima/0	involves: C57BL/6J	MGI:3834683

Genotype
MGI:3834683

tg1

• Allelic Composition: Tg(SFTPC-EML4/ALK)502-4Hima/0
• Genetic Background: involves: C57BL/6J

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

neoplasm

increased lung adenocarcinoma incidence ( J:142679 )

• mice develop lung adenocarcinoma a few weeks after birth

• however, treatment with an ALK inhibitor reduces tumor burden

respiratory system

increased lung adenocarcinoma incidence ( J:142679 )

• mice develop lung adenocarcinoma a few weeks after birth

• however, treatment with an ALK inhibitor reduces tumor burden

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
lung cancer		DOID:1324	OMIM:211980 OMIM:608935 OMIM:612571 OMIM:612593 OMIM:614210	J:142679