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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Ngfrtm1Klee
targeted mutation 1, Kuo-Fen Lee
MGI:3835477
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cn1
 		Gt(ROSA)26Sortm1(GAP43/EGFP)Gld/Gt(ROSA)26Sor+
Ngfrtm1Klee/Ngfrtm1Klee
Tg(Pax6-cre,GFP)2Pgr/0 		involves: 129S1/Sv MGI:3835510


Genotype
MGI:3835510
cn1
Allelic
Composition		 Gt(ROSA)26Sortm1(GAP43/EGFP)Gld/Gt(ROSA)26Sor+
Ngfrtm1Klee/Ngfrtm1Klee
Tg(Pax6-cre,GFP)2Pgr/0
Genetic
Background		 involves: 129S1/Sv
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gt(ROSA)26Sortm1(GAP43/EGFP)Gld mutation (0 available); any Gt(ROSA)26Sor mutation (993 available)
Ngfrtm1Klee mutation (0 available); any Ngfr mutation (33 available)
Tg(Pax6-cre,GFP)2Pgr mutation (1 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
abnormal superior colliculus morphology ( J:145459 )
• the nasal domain of retinal axon termination zone is expanded anteriorly compared to in wild-type mice
abnormal retina ganglion cell morphology ( J:145459 )
• the nasal domain of retinal axon termination zone is expanded anteriorly compared to in wild-type mice

vision/eye
vision/eye phenotype ( J:145459 )
N
• retinal development, size, and patterning are normal
abnormal retina ganglion cell morphology ( J:145459 )
• the nasal domain of retinal axon termination zone is expanded anteriorly compared to in wild-type mice




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory