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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Bxs6BXSB/MpJ
BXSB/MpJ
MGI:3836289
Summary 4 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Bxs6BXSB/MpJ/Bxs6BXSB/MpJ B10.BXSB-(D13Mit3-D13Mit78) MGI:3836734
hm2
 		Bxs6BXSB/MpJ/Bxs6BXSB/MpJ involves: BXSB/MpJ * C57BL/10ScSnOlaHsd MGI:3836614
cx3
 		Bxs6BXSB/MpJ/Bxs6BXSB/MpJ
X/Yaa 		B10.BXSB-(D13Mit3-D13Mit78) Yaa MGI:3836730
cx4
 		Bxs6BXSB/MpJ/Bxs6BXSB/MpJ
Gpab1C57BL/6J/? 		involves: BXSB/MpJ * C57BL/10ScSnOlaHsd MGI:3836615


Genotype
MGI:3836734
hm1
Allelic
Composition		 Bxs6BXSB/MpJ/Bxs6BXSB/MpJ
Genetic
Background		 B10.BXSB-(D13Mit3-D13Mit78)
Find Mice Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
autoimmune response ( J:145049 )
• increased levels of gp70 immune complex formation
increased autoantibody level ( J:145049 )
• increased gp70 autoimmune antibody titers




Genotype
MGI:3836614
hm2
Allelic
Composition		 Bxs6BXSB/MpJ/Bxs6BXSB/MpJ
Genetic
Background		 involves: BXSB/MpJ * C57BL/10ScSnOlaHsd
Find Mice Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
autoimmune response ( J:145903 )
• increased levels of gp70 immune complex
increased autoantibody level ( J:145903 )
• increased titers of gp70 autoantibodies
glomerulonephritis ( J:145903 )
• increased glomerulonephritis severity

renal/urinary system
glomerulonephritis ( J:145903 )
• increased glomerulonephritis severity




Genotype
MGI:3836730
cx3
Allelic
Composition		 Bxs6BXSB/MpJ/Bxs6BXSB/MpJ
X/Yaa
Genetic
Background		 B10.BXSB-(D13Mit3-D13Mit78) Yaa
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Bxs6BXSB/MpJ mutation (0 available); any Bxs6 mutation (0 available)
Yaa mutation (24 available); any Yaa mutation (27 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
autoimmune response ( J:145049 )
• increased levels of gp70 immune complex formation
increased autoantibody level ( J:145049 )
• increased gp70 autoantibody titers
glomerulonephritis ( J:145049 )
• increased glomerulonephritis incidence and severity
• decreased survival

hematopoietic system

renal/urinary system
glomerulonephritis ( J:145049 )
• increased glomerulonephritis incidence and severity
• decreased survival

growth/size/body
enlarged spleen ( J:145049 )




Genotype
MGI:3836615
cx4
Allelic
Composition		 Bxs6BXSB/MpJ/Bxs6BXSB/MpJ
Gpab1C57BL/6J/?
Genetic
Background		 involves: BXSB/MpJ * C57BL/10ScSnOlaHsd
Find Mice Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
autoimmune response ( J:145903 )
• increased levels of gp70 immune complex
increased autoantibody level ( J:145903 )
• increased titers of gp70 autoantibodies




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/17/2024
MGI 6.24 		The Jackson Laboratory