Phenotypes associated with this allele

• Allele Symbol: Tg(ACTB-Twnk*A360T)HSuom
• Allele Name: transgene insertion H, Anu Suomalainen
• Allele ID: MGI:3836898
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
tg1	Tg(ACTB-Twnk*A360T)HSuom/0	involves: FVB/N	MGI:3836900

Genotype
MGI:3836900

tg1

• Allelic Composition: Tg(ACTB-Twnk*A360T)HSuom/0
• Genetic Background: involves: FVB/N

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

mortality/aging ( J:104378 )

N • mice exhibit normal aging and life span

cellular

abnormal mitochondrial physiology ( J:104378 )

• at 18 months, mice exhibit a few COX- muscle fibers, indicating reduced mitochondrial function, unlike in wild-type mice

• however, total respiration capacity of the muscle is normal

muscle

muscle phenotype ( J:104378 )

N • despite mitochondrial defects, mice exhibit normal muscle strength and performance

abnormal muscle fiber morphology ( J:104378 )

• at 18 months, mice exhibit a few COX- muscle fibers, indicating reduced mitochondrial function, unlike in wild-type mice

• however, total respiration capacity of the muscle is normal

behavior/neurological

behavior/neurological phenotype ( J:104378 )

N • despite mitochondrial defects, mice exhibit normal muscle strength and performance