Phenotypes associated with this allele

• Allele Symbol: Tg(PER2*S662G)867Ljp
• Allele Name: transgene insertion 867, Louis J Ptacek
• Allele ID: MGI:3837437
• Summary: 4 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
cx1	Csnk1d^Gt(TEA020)Byg/Csnk1d^+ Tg(PER2*S662G)867Ljp/0	involves: 129P2/OlaHsd * C57BL/6	MGI:3852105
cx2	Per2^tm1Drw/Per2^tm1Drw Tg(PER2*S662G)867Ljp/0	involves: C57BL/6	MGI:3852104
cx3	Tg(CSNK1D,-EGFP)#Yfu/0 Tg(PER2*S662G)867Ljp/0	involves: C57BL/6	MGI:3852108
tg4	Tg(PER2*S662G)867Ljp/0	involves: C57BL/6	MGI:3852102

Genotype
MGI:3852105

cx1

• Allelic Composition: Csnk1d^{Gt(TEA020)Byg}/Csnk1d⁺; Tg(PER2*S662G)867Ljp/0
• Genetic Background: involves: 129P2/OlaHsd * C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

shortened circadian behavior period ( J:126404 )

• circadian period is shortened 1.5 hours compared to in wild-type mice

Genotype
MGI:3852104

cx2

• Allelic Composition: Per2^tm1Drw/Per2^tm1Drw; Tg(PER2*S662G)867Ljp/0
• Genetic Background: involves: C57BL/6

behavior/neurological

shortened circadian behavior period ( J:126404 )

• circadian period is shortened 3.3 hours compared to in wild-type mice

• however, mice under LD10.5:10.5 conditions exhibit normal on-off activity patterns

Genotype
MGI:3852108

cx3

• Allelic Composition: Tg(CSNK1D,-EGFP)#Yfu/0; Tg(PER2*S662G)867Ljp/0
• Genetic Background: involves: C57BL/6

behavior/neurological

shortened circadian behavior period ( J:126404 )

• circadian period is shortened 3.2 hours compared to in wild-type mice

Genotype
MGI:3852102

tg4

• Allelic Composition: Tg(PER2*S662G)867Ljp/0
• Genetic Background: involves: C57BL/6

behavior/neurological

prolonged circadian behavior period ( J:126404 )

• circadian period is 0.7 hours longer than in wild-type mice

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
advanced sleep phase syndrome 1		DOID:0110011	OMIM:604348	J:126404