homeostasis/metabolism
• when treated with MC903 mice develop dry and scaly ears unlike similarly treated mice that develop red or inflamed lesions
• MC903-treated ears exhibit some the epidermal hyperplasia but not the heavy dermal cell infiltrate observed as in similarly treated wild-type mice
• at day 16 following application of MC903, mice exhibit a lesser increase in IgE levels compared to in similarly treated wild-type mice
• MC903-treated mice fail to exhibit an increase in eosinophil and lymphocyte counts compared to in similarly treated wild-type mice
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immune system
• MC903-treated mice fail to exhibit an increase in eosinophil and lymphocyte counts compared to in similarly treated wild-type mice
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• MC903-treated mice fail to exhibit an increase in eosinophil and lymphocyte counts compared to in similarly treated wild-type mice
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• compared to in wild-type mice at day 16 following application of MC903
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hematopoietic system
• MC903-treated mice fail to exhibit an increase in eosinophil and lymphocyte counts compared to in similarly treated wild-type mice
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• MC903-treated mice fail to exhibit an increase in eosinophil and lymphocyte counts compared to in similarly treated wild-type mice
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• compared to in wild-type mice at day 16 following application of MC903
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