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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Atf6tm1Kamo
targeted mutation 1, Kazutoshi Mori
MGI:3839240
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Atf6tm1Kamo/Atf6tm1Kamo involves: 129S4/SvJae * C57BL/6J MGI:3839245
cx2
 		Atf6tm1Kamo/Atf6tm1Kamo
Atf6btm1Kamo/Atf6btm1Kamo 		involves: 129S4/SvJae * C57BL/6J MGI:3839247


Genotype
MGI:3839245
hm1
Allelic
Composition		 Atf6tm1Kamo/Atf6tm1Kamo
Genetic
Background		 involves: 129S4/SvJae * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Atf6tm1Kamo mutation (1 available); any Atf6 mutation (45 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cellular
increased sensitivity to induced cell death ( J:145116 )
• mouse embryonic fibroblasts (MEFs) are slightly more sensitive to tunicamycin- or thapsigargin-treatment compared to wild-type cells




Genotype
MGI:3839247
cx2
Allelic
Composition		 Atf6tm1Kamo/Atf6tm1Kamo
Atf6btm1Kamo/Atf6btm1Kamo
Genetic
Background		 involves: 129S4/SvJae * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Atf6btm1Kamo mutation (1 available); any Atf6b mutation (43 available)
Atf6tm1Kamo mutation (1 available); any Atf6 mutation (45 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory