About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Aicdatm4.1Mnz
targeted mutation 4.1, Michel C Nussenzweig
MGI:3839323
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Aicdatm4.1Mnz/Aicdatm4.1Mnz involves: C57BL/6 MGI:3839353


Genotype
MGI:3839353
hm1
Allelic
Composition		 Aicdatm4.1Mnz/Aicdatm4.1Mnz
Genetic
Background		 involves: C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Aicdatm4.1Mnz mutation (1 available); any Aicda mutation (57 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hematopoietic system
abnormal class switch recombination ( J:147109 )
• B cells have impaired ability to undergo class switch recombination
abnormal somatic hypermutation frequency ( J:147109 )
• B cells have impaired ability to undergo somatic hypermutation

immune system
abnormal class switch recombination ( J:147109 )
• B cells have impaired ability to undergo class switch recombination
abnormal somatic hypermutation frequency ( J:147109 )
• B cells have impaired ability to undergo somatic hypermutation




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory