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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Aicdatm4.1Mnz
targeted mutation 4.1, Michel C Nussenzweig
MGI:3839323
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Aicdatm4.1Mnz/Aicdatm4.1Mnz involves: C57BL/6 MGI:3839353


Genotype
MGI:3839353
hm1
Allelic
Composition		 Aicdatm4.1Mnz/Aicdatm4.1Mnz
Genetic
Background		 involves: C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Aicdatm4.1Mnz mutation (1 available); any Aicda mutation (57 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hematopoietic system
abnormal class switch recombination ( J:147109 )
• B cells have impaired ability to undergo class switch recombination
abnormal somatic hypermutation frequency ( J:147109 )
• B cells have impaired ability to undergo somatic hypermutation

immune system
abnormal class switch recombination ( J:147109 )
• B cells have impaired ability to undergo class switch recombination
abnormal somatic hypermutation frequency ( J:147109 )
• B cells have impaired ability to undergo somatic hypermutation




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory