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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		E2f3tm3Lees
targeted mutation 3, Jacqueline A Lees
MGI:3840181
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		E2f3tm3Lees/E2f3tm3Lees either: 129S/Sv-E2f3tm3Lees or (involves: 129S4/SvJae * C57BL/6) MGI:3840226
cx2
 		E2f1tm1Njd/E2f1tm1Njd
E2f3tm3Lees/E2f3tm3Lees 		involves: 129S2/SvPas * 129S4/SvJae * C57BL/6 MGI:3840229


Genotype
MGI:3840226
hm1
Allelic
Composition		 E2f3tm3Lees/E2f3tm3Lees
Genetic
Background		 either: 129S/Sv-E2f3tm3Lees or (involves: 129S4/SvJae * C57BL/6)
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
E2f3tm3Lees mutation (0 available); any E2f3 mutation (33 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
normal phenotype
no abnormal phenotype detected ( J:147270 )
• cell cycle regulation is normal
• mice are viable and fertile




Genotype
MGI:3840229
cx2
Allelic
Composition		 E2f1tm1Njd/E2f1tm1Njd
E2f3tm3Lees/E2f3tm3Lees
Genetic
Background		 involves: 129S2/SvPas * 129S4/SvJae * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
E2f1tm1Njd mutation (1 available); any E2f1 mutation (28 available)
E2f3tm3Lees mutation (0 available); any E2f3 mutation (33 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
normal phenotype
no abnormal phenotype detected ( J:147270 )
• no affect on viability to weaning
• fertility is normal




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory