Analysis Tools
mortality/aging
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• mice die between E9.5 and E10.5
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embryo
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• at E9.5 all mice are severely abnormal and indistinguishable from Axin1Fu-Tg1 homozygotes
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• mice fail to turn
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• developmental delay at E9.5
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• at E9.5
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• the head folds are open and shortened compared to in wild-type mice
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cardiovascular system
nervous system
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• the head folds are open and shortened compared to in wild-type mice
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craniofacial
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• truncated head at E9.5
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growth/size/body
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• truncated head at E9.5
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• developmental delay at E9.5
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• at E9.5
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• mice exhibit underdeveloped trunks compared to wild-type mice
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