Analysis Tools|
Allele Symbol Allele Name Allele ID |
Ccn2tm1Mga targeted mutation 1, Maureen Gannon MGI:3840270 |
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| Summary |
3 genotypes
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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• the phenotype is said to be identical to that of mice homozygous for Ctgftm1Kml
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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• at 1 month of age the bone volume to tissue volume ratio is reduced by 30-45%
• however, by 4 and 6 months of age no difference in the bone volume to tissue volume ratio is detected
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• at 1 month of age the number of trabeculae is reduced but trabecular thickness is not significantly reduced
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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• at 1 month of age osteopenia is seen
• at 1 month of age the phenotype is similar to that in Ctgftm1Mga single homozygotes
• at 6 months of age males show a decrease in bone volume secondary to a decrease in trabecular number
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• at 1 month and 6 months of age the number of trabeculae is reduced
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 12/10/2024 MGI 6.24 |
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