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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Del(7Tyrobp-Hcst)1Ttk
deletion, Chr 7, Toshiyuki Takai 1
MGI:3840566
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Del(7Tyrobp-Hcst)1Ttk/Del(7Tyrobp-Hcst)1Ttk B6.129X1-Del(7Tyrobp-Hcst)1Ttk MGI:3840590
cx2
 		Fcer1gtm1Rav/Fcer1gtm1Rav
Del(7Tyrobp-Hcst)1Ttk/Del(7Tyrobp-Hcst)1Ttk 		involves: 129P2/OlaHsd * 129X1/SvJ * C57BL/6 MGI:3840594


Genotype
MGI:3840590
hm1
Allelic
Composition		 Del(7Tyrobp-Hcst)1Ttk/Del(7Tyrobp-Hcst)1Ttk
Genetic
Background		 B6.129X1-Del(7Tyrobp-Hcst)1Ttk
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Del(7Tyrobp-Hcst)1Ttk mutation (1 available); any Del(7Tyrobp-Hcst)1Ttk mutation (0 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
skeleton
skeleton phenotype ( J:147155 )
N
• at 3 months of age, mice exhibit normal numbers of TRAP+ osteoclasts are observed




Genotype
MGI:3840594
cx2
Allelic
Composition		 Fcer1gtm1Rav/Fcer1gtm1Rav
Del(7Tyrobp-Hcst)1Ttk/Del(7Tyrobp-Hcst)1Ttk
Genetic
Background		 involves: 129P2/OlaHsd * 129X1/SvJ * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Del(7Tyrobp-Hcst)1Ttk mutation (1 available); any Del(7Tyrobp-Hcst)1Ttk mutation (0 available)
Fcer1gtm1Rav mutation (8 available); any Fcer1g mutation (28 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
skeleton
abnormal osteoclast physiology ( J:147155 )
• fewer tartrate-resistant acid phosphatase (TRAP)+ osteoclasts are observed compared to in wild-type mice

immune system
abnormal osteoclast physiology ( J:147155 )
• fewer tartrate-resistant acid phosphatase (TRAP)+ osteoclasts are observed compared to in wild-type mice

hematopoietic system
abnormal osteoclast physiology ( J:147155 )
• fewer tartrate-resistant acid phosphatase (TRAP)+ osteoclasts are observed compared to in wild-type mice




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory