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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Tcra-Jtm5Krg
targeted mutation 5, Michael S Krangel
MGI:3840778
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Tcra-Jtm5Krg/Tcra-Jtm5Krg involves: 129S6/SvEvTac MGI:3840784


Genotype
MGI:3840784
hm1
Allelic
Composition
Tcra-Jtm5Krg/Tcra-Jtm5Krg
Genetic
Background
involves: 129S6/SvEvTac
Find Mice Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.
phenotype observed in females
phenotype observed in males
N normal phenotype
immune system
• use of Jalpha segments 56-58 in recombined Tcra transcripts is 1% of that found in wild-type thymocytes
• use of the Jalpha53 segment is about 10% of wild-type and use of the Jalpha52 segment is about 30% of wild-type
• the use of Jalpha 50 and other Jalpha segments further downstream is normal

hematopoietic system
• use of Jalpha segments 56-58 in recombined Tcra transcripts is 1% of that found in wild-type thymocytes
• use of the Jalpha53 segment is about 10% of wild-type and use of the Jalpha52 segment is about 30% of wild-type
• the use of Jalpha 50 and other Jalpha segments further downstream is normal





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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory