Phenotypes associated with this allele

• Allele Symbol: Slc34a2^tm1Khan
• Allele Name: targeted mutation 1, Kazunori Hanaoka
• Allele ID: MGI:3841013
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Slc34a2^tm1Khan/Slc34a2^tm1Khan	involves: C57BL/6 * CBA	MGI:3841014

Genotype
MGI:3841014

hm1

• Allelic Composition: Slc34a2^tm1Khan/Slc34a2^tm1Khan
• Genetic Background: involves: C57BL/6 * CBA

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

embryonic lethality during organogenesis, complete penetrance ( J:147386 )

• no viable embryos are found after E11.5

embryonic lethality between somite formation and embryo turning, incomplete penetrance ( J:147386 )

• lethality is observed beginning at E8.0

embryo

failure of initiation of embryo turning ( J:147386 )

• do not show signs of axial rotation at E9.5

embryonic growth arrest ( J:147386 )

• at E8.0

decreased embryo size ( J:147386 )

• at E8.0

failure of somite differentiation ( J:147386 )

• do not show signs of somitogenesis at E9.5

abnormal extraembryonic tissue morphology ( J:147386 )

absent placental labyrinth ( J:147386 )

• chorionic trophoblasts fail to form the labyrinth layer

failure of chorioallantoic fusion ( J:147386 )

• a chorio-allantois is barely formed at E9.0 - E9.5

abnormal vitelline vascular remodeling ( J:147386 )

• the vascular plexus forms but subsequent remodeling is impaired with a honeycomb like plexus still present at E9.0 - E9.5

growth/size/body

decreased embryo size ( J:147386 )

• at E8.0