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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Tg(BCL2)#Wehi
transgene insertion, Walter and Eliza Hall Institute of Medical Research
MGI:3842923
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cn1
 		Ebf1tm1.1Rug/Ebf1tm1.1Rug
Polr2atm1(cre/ERT2)Bbd/Polr2a+
Tg(BCL2)#Wehi/0 		involves: C57BL/6 * C57BL/6JWehi * SJL * SJL/JWehi MGI:5316372


Genotype
MGI:5316372
cn1
Allelic
Composition		 Ebf1tm1.1Rug/Ebf1tm1.1Rug
Polr2atm1(cre/ERT2)Bbd/Polr2a+
Tg(BCL2)#Wehi/0
Genetic
Background		 involves: C57BL/6 * C57BL/6JWehi * SJL * SJL/JWehi
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ebf1tm1.1Rug mutation (0 available); any Ebf1 mutation (74 available)
Polr2atm1(cre/ERT2)Bbd mutation (3 available); any Polr2a mutation (92 available)
Tg(BCL2)#Wehi mutation (0 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
decreased immature B cell number ( J:182210 )
• fewer CD25-kappa+ immature B cells in tamoxifen-treated mice
decreased pre-B cell number ( J:182210 )
• fewer CD25+kappa- pre-B cells in tamoxifen-treated mice

hematopoietic system
decreased immature B cell number ( J:182210 )
• fewer CD25-kappa+ immature B cells in tamoxifen-treated mice
decreased pre-B cell number ( J:182210 )
• fewer CD25+kappa- pre-B cells in tamoxifen-treated mice




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory