Phenotypes associated with this allele

• Allele Symbol: Rbm19^Gt(XC768)Byg
• Allele Name: gene trap XC768, BayGenomics
• Allele ID: MGI:3843656
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Rbm19^Gt(XC768)Byg/Rbm19^Gt(XC768)Byg	involves: 129P2/OlaHsd	MGI:3843665

Genotype
MGI:3843665

hm1

• Allelic Composition: Rbm19^Gt(XC768)Byg/Rbm19^Gt(XC768)Byg
• Genetic Background: involves: 129P2/OlaHsd

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

embryonic lethality before implantation, complete penetrance ( J:145174 )

• while present at E3.5, no embryos are detected at E6.5

• embryos fail to develop beyond the morula stage

embryo

abnormal preimplantation embryo development ( J:145174 )

failure of morula compaction ( J:145174 )

• morulas fail to undergo compaction and apoptose

embryonic growth arrest ( J:145174 )

• at E3.5, embryos have not progressed beyond the morula stage and fail to do so when cultured unlike wild-type embryos

cellular

abnormal cell nucleus morphology ( J:145174 )

• E3.5 cells fail to form a mature, tripartite nucleoli unlike wild-type cells