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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Hvcn1Gt(RRN293)Byg
gene trap RRN293, BayGenomics
MGI:3843777
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Hvcn1Gt(RRN293)Byg/Hvcn1Gt(RRN293)Byg B6.129P2-Hvcn1Gt(RRN293)Byg MGI:3843781


Genotype
MGI:3843781
hm1
Allelic
Composition		 Hvcn1Gt(RRN293)Byg/Hvcn1Gt(RRN293)Byg
Genetic
Background		 B6.129P2-Hvcn1Gt(RRN293)Byg
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Hvcn1Gt(RRN293)Byg mutation (1 available); any Hvcn1 mutation (30 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
abnormal neutrophil physiology ( J:148032 )
• neutrophils lack voltage-gated proton currents unlike wild-type cells
abnormal macrophage physiology ( J:148032 )
• macrophages lack voltage-gated proton currents unlike wild-type cells

hematopoietic system
abnormal neutrophil physiology ( J:148032 )
• neutrophils lack voltage-gated proton currents unlike wild-type cells
abnormal macrophage physiology ( J:148032 )
• macrophages lack voltage-gated proton currents unlike wild-type cells




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory