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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Tg(Prkcd-glc-1/CFP,-cre)EH124Gsat
transgene insertion EH124, GENSAT Project at Rockefeller University
MGI:3844446
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
cn1
Eef1a1tm1Klan/Eef1a1tm1Klan
Tg(Prkcd-glc-1/CFP,-cre)EH124Gsat/0
involves: 129S6/SvEvTac * C57BL/6J * FVB/NTac MGI:6693448
cn2
Col1a1tm1(tetO-GFP,-RNAi:Eef1a1)Mcg/Col1a1+
Tg(Prkcd-glc-1/CFP,-cre)EH124Gsat/0
involves: C57BL/6J * FVB/NTac MGI:6693444


Genotype
MGI:6693448
cn1
Allelic
Composition
Eef1a1tm1Klan/Eef1a1tm1Klan
Tg(Prkcd-glc-1/CFP,-cre)EH124Gsat/0
Genetic
Background
involves: 129S6/SvEvTac * C57BL/6J * FVB/NTac
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Eef1a1tm1Klan mutation (1 available); any Eef1a1 mutation (60 available)
Tg(Prkcd-glc-1/CFP,-cre)EH124Gsat mutation (1 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
behavior/neurological
• mice infusion with asunaprivir (drug inducer of iPKR) exhibit impaired conditioned safety response to withdrawal of cued stimuli compared with wild-type mice
• however, acquisition of differential threat associative memory is normal




Genotype
MGI:6693444
cn2
Allelic
Composition
Col1a1tm1(tetO-GFP,-RNAi:Eef1a1)Mcg/Col1a1+
Tg(Prkcd-glc-1/CFP,-cre)EH124Gsat/0
Genetic
Background
involves: C57BL/6J * FVB/NTac
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Col1a1tm1(tetO-GFP,-RNAi:Eef1a1)Mcg mutation (0 available); any Col1a1 mutation (163 available)
Tg(Prkcd-glc-1/CFP,-cre)EH124Gsat mutation (1 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
behavior/neurological
• mice virally expressing a cre-dependent tet transactivator exhibit impaired conditioned safety response to withdrawal of cued stimuli compared with wild-type mice
• however, acquisition of differential threat associative memory is normal
• increased exploration of an elevated plus maze in mice virally expressing a cre-dependent tet transactivator





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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory