Analysis Tools
cardiovascular system
|
• hypertrophy of cardiomyocytes occurs after 6 weeks of aortic banding to mice that have had cre expression induced
|
|
• left ventricular end systolic volume is increased after cre induction from 0.017 cm3/g to 0.021 cm3/g
|
|
• after cre induction, the left ventricular ejection fraction is depressed from 0.65 cm3/g to 0.60 cm3/g
|
|
• heart rate is depressed after cre induction from 443 bpm to 441 bpm
|
|
• male mice with cre induction and intracardiac electrical stimulation have more ventricular tachycardia episodes than controls (17 vs. 3)
• duration of these episodes are also about 3-fold longer than controls
|
growth/size/body
weight loss
(
J:148331
)
|
• mice in which cre expression is induced have more weight loss than controls in response to exercise
|
homeostasis/metabolism
|
• mice with cre expression have a reduced exercise capacity
|
muscle
|
• hypertrophy of cardiomyocytes occurs after 6 weeks of aortic banding to mice that have had cre expression induced
|
|
• after cre induction, the left ventricular ejection fraction is depressed from 0.65 cm3/g to 0.60 cm3/g
|
behavior/neurological
|
• mice with cre expression have a reduced exercise capacity
|
