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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Tsed
twisted legs and extra digits
MGI:3845084
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Tsed/Tsed STOCK Tsed/GrsrJ MGI:5485245
ht2
 		Tsed/Tsed+ STOCK Tsed/GrsrJ MGI:5485254


Genotype
MGI:5485245
hm1
Allelic
Composition		 Tsed/Tsed
Genetic
Background		 STOCK Tsed/GrsrJ
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tsed mutation (1 available); any Tsed mutation (1 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype

Tsed/Tsed mice have polydactyly on all four feet

limbs/digits/tail
polydactyly ( J:195767 )
• significant polydactyly is found on all four feet
abnormal hindlimb morphology ( J:195767 )
• bowed long bones make the hind legs twist inward toward the body in many, but not all mutants




Genotype
MGI:5485254
ht2
Allelic
Composition		 Tsed/Tsed+
Genetic
Background		 STOCK Tsed/GrsrJ
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tsed mutation (1 available); any Tsed mutation (1 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
limbs/digits/tail
polydactyly ( J:195767 )
• Background Sensitivity: significant polydactyly is found on all four feet of most heterozygotes, but when outcrossed to BALB/cByJ penetrance is incomplete in the heterozygote
abnormal hindlimb morphology ( J:195767 )
• twisted hindlegs due to bowed long bones is found in some heterozygotes




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory