About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Six2tm2(cre/ERT2)Amc
targeted mutation 2, Andrew P McMahon
MGI:3845219
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Six2tm2(cre/ERT2)Amc/Six2tm2(cre/ERT2)Amc involves: 129S4/SvJae * C57BL/6J MGI:3848502
ht2
 		Six2tm2(cre/ERT2)Amc/Six2+ involves: 129S4/SvJae * C57BL/6J MGI:3848501


Genotype
MGI:3848502
hm1
Allelic
Composition		 Six2tm2(cre/ERT2)Amc/Six2tm2(cre/ERT2)Amc
Genetic
Background		 involves: 129S4/SvJae * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Six2tm2(cre/ERT2)Amc mutation (1 available); any Six2 mutation (15 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
neonatal lethality, complete penetrance ( J:148455 )
• mice die shortly after birth




Genotype
MGI:3848501
ht2
Allelic
Composition		 Six2tm2(cre/ERT2)Amc/Six2+
Genetic
Background		 involves: 129S4/SvJae * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Six2tm2(cre/ERT2)Amc mutation (1 available); any Six2 mutation (15 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
normal phenotype
no abnormal phenotype detected ( J:148455 )
• mice are viable, fertile, and display no obvious abnormalities




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
10/09/2024
MGI 6.24 		The Jackson Laboratory