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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Tg(FCER1A)1Bhk
transgene insertion 1, Beverly H Koller
MGI:3846551
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cx1
 		Fcer1atm1Knt/Fcer1atm1Knt
Tg(FCER1A)1Bhk/? 		B6.129-Fcer1atm1Knt Tg(FCER1A)1Bhk MGI:3851203


Genotype
MGI:3851203
cx1
Allelic
Composition		 Fcer1atm1Knt/Fcer1atm1Knt
Tg(FCER1A)1Bhk/?
Genetic
Background		 B6.129-Fcer1atm1Knt Tg(FCER1A)1Bhk
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Fcer1atm1Knt mutation (3 available); any Fcer1a mutation (23 available)
Tg(FCER1A)1Bhk mutation (1 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
abnormal macrophage physiology ( J:144620 )
• macrophages secrete higher levels of TNF in response to IgE complexes compared to controls
increased tumor necrosis factor secretion ( J:144620 )
• macrophages secrete higher levels of TNF in response to IgE complexes compared to controls

hematopoietic system
abnormal macrophage physiology ( J:144620 )
• macrophages secrete higher levels of TNF in response to IgE complexes compared to controls




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory