All Phenotypes Vash1<tm1Ysat> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Vash1^tm1Ysat
targeted mutation 1, Yasufumi Sato
MGI:3846783

Summary

2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Vash1^tm1Ysat/Vash1^tm1Ysat	involves: C57BL/6	MGI:3846787
ht2	Vash1^tm1Ysat/Vash1⁺	involves: C57BL/6	MGI:3846788

Allelic Composition	Vash1^tm1Ysat/Vash1^tm1Ysat
Genetic Background	involves: C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Vash1^tm1Ysat mutation (0 available); any Vash1 mutation (20 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

cardiovascular system

increased angiogenesis ( J:148726 )

• mice have an increased area of vascularized tissue in the termination zone that lies a distance from a necrotic wound where angiogenesis is normally inhibited

• vascularized area is about 4 times greater 6-8 mm from the wound edge compared to controls

Allelic Composition	Vash1^tm1Ysat/Vash1⁺
Genetic Background	involves: C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Vash1^tm1Ysat mutation (0 available); any Vash1 mutation (20 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

cardiovascular system

increased angiogenesis ( J:148726 )

• mice have an increased area of vascularized tissue in the termination zone that lies a distance from a necrotic wound where angiogenesis is normally inhibited

• vascularized area is not as great as observed in Vash1^tm1Ysa homozygotes

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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