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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Tsc22d1tm1Clgr
targeted mutation 1, Michael Caligiuri
MGI:3847243
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Tsc22d1tm1Clgr/Tsc22d1tm1Clgr B6.129P2-Tsc22d1tm1Clgr MGI:3847248


Genotype
MGI:3847248
hm1
Allelic
Composition		 Tsc22d1tm1Clgr/Tsc22d1tm1Clgr
Genetic
Background		 B6.129P2-Tsc22d1tm1Clgr
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tsc22d1tm1Clgr mutation (0 available); any Tsc22d1 mutation (90 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hematopoietic system
abnormal bone marrow cell physiology ( J:148897 )
• proliferation of Lin- CD117+ bone marrow cells is increased compared with proliferation of wild-type cells
• bone marrow cells exhibit higher repopulation efficiency than wild-type cell in transplant assays

cardiovascular system
decreased heart weight ( J:148897 )
• 13% to 15%

renal/urinary system




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
10/29/2024
MGI 6.24 		The Jackson Laboratory